what is Abilify (by AI)
Abilify (generic name: aripiprazole) is an antipsychotic medication used to treat a variety of mental health conditions. It belongs to the class of atypical antipsychotics.
Main Uses
Abilify is FDA-approved for the treatment of:
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Schizophrenia (in adults and adolescents age 13+)
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Bipolar I disorder (as monotherapy or with lithium/valproate; for manic/mixed episodes)
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Major depressive disorder (MDD) – as an add-on to antidepressants
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Irritability associated with autism (in children 6–17)
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Tourette's disorder (in children 6–18)
How It Works
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Aripiprazole acts as a partial agonist at dopamine D2 receptors and serotonin 5-HT1A receptors, and as an antagonist at 5-HT2A receptors.
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This helps balance dopamine and serotonin activity in the brain, which can help stabilize mood, behavior, and thinking.
Common Side Effects
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Akathisia (inner restlessness)
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Insomnia
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Nausea
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Anxiety
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Weight gain (less than other atypical antipsychotics)
Warnings
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Boxed warning for increased risk of death in elderly patients with dementia-related psychosis.
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Risk of suicidal thoughts in children, adolescents, and young adults.
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