what is Abilify (by AI)

 Abilify (generic name: aripiprazole) is an antipsychotic medication used to treat a variety of mental health conditions. It belongs to the class of atypical antipsychotics.


Main Uses

Abilify is FDA-approved for the treatment of:

  • Schizophrenia (in adults and adolescents age 13+)

  • Bipolar I disorder (as monotherapy or with lithium/valproate; for manic/mixed episodes)

  • Major depressive disorder (MDD)as an add-on to antidepressants

  • Irritability associated with autism (in children 6–17)

  • Tourette's disorder (in children 6–18)


How It Works

  • Aripiprazole acts as a partial agonist at dopamine D2 receptors and serotonin 5-HT1A receptors, and as an antagonist at 5-HT2A receptors.

  • This helps balance dopamine and serotonin activity in the brain, which can help stabilize mood, behavior, and thinking.


Common Side Effects

  • Akathisia (inner restlessness)

  • Insomnia

  • Nausea

  • Anxiety

  • Weight gain (less than other atypical antipsychotics)


Warnings

  • Boxed warning for increased risk of death in elderly patients with dementia-related psychosis.

  • Risk of suicidal thoughts in children, adolescents, and young adults.

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