100 multiple-choice questions (MCQs) based on Chapter 9: Fever from DiPiro’s Pharmacotherapy, 12th Edition Nehad J. Ahmed Written using Grok
100
multiple-choice questions (MCQs) based on Chapter 9: Fever from DiPiro’s
Pharmacotherapy, 12th Edition
Nehad J. Ahmed
Written using Grok
What is fever defined
as in the chapter?
A. An uncontrolled
rise in body temperature
B. A controlled
elevation of body temperature above normal range
C. A decrease in
hypothalamic set point
D. Normal body
temperature fluctuation
E. Hyperthermia due to
environmental exposure
Correct: B
Where is body
temperature regulated?
A. Posterior
hypothalamus
B. Anterior
hypothalamus
C. Cerebral cortex
D. Medulla oblongata
E. Pituitary gland
Correct: B
What causes an
increase in the hypothalamic temperature set point during fever?
A. Decreased
prostaglandin production
B. Prostaglandins
C. Reduced heat
production in periphery
D. Lowered circadian
rhythm
E. Dehydration
Correct: B
According to key
concepts, what should healthcare professionals COLLECT for fever assessment?
A. Only temperature
logs
B. Key information on
medications, history, immunizations, travel, etc.
C. Only recent
vaccinations
D. Only social history
E. Only barriers to
care
Correct: B
What is the preferred
agent to reduce fever in most patients?
A. Ibuprofen
B. Aspirin
C. Acetaminophen
D. Naproxen
E. NSAIDs only
Correct: C
When should medical
evaluation be sought for fever in adults?
A. Within 24 hours
B. Within 48 hours
C. If no resolution
within 3 days
D. Within 1 week
E. Only if above 41°C
Correct: C
In the Patient Care
Process, what is included in the COLLECT phase?
A. Developing a care
plan
B. Patient
demographics, medication history, immunizations, etc.
C. Assessing
differential diagnosis
D. Implementing
therapy
E. Follow-up
monitoring
Correct: B
What should be
assessed to differentiate fever from hyperthermia?
A. Response to
antipyretics
B. Only temperature
readings
C. Only travel history
D. Only medication
list
E. Only social
activities
Correct: A
Goals of therapy for
fever include:
A. Increasing body
temperature
B. Relieving
discomfort and reducing temperature
C. Ignoring underlying
cause
D. Using only nondrug
treatments
E. Avoiding hydration
Correct: B
Nondrug treatments for
fever include:
A. Alcohol baths
B. Ice baths
C. Cooling blankets
with antipyretics
D. Tight clothing
E. Reduced fluid
intake
Correct: C
Why are NSAIDs not
always preferred for fever?
A. They increase
prostaglandins
B. Adverse effects on
GI tract and platelets
C. They cause
hyperthermia
D. They are
ineffective
E. They lower set
point too much
Correct: B
For children younger
than 2 years, seek medical care if no resolution within:
A. 3 days
B. 48 hours
C. 24 hours
D. 1 week
E. 12 hours
Correct: C
Fever is the leading
cause of emergency visits in patients younger than:
A. 5 years
B. 10 years
C. 15 years
D. 20 years
E. 25 years
Correct: C
Normal oral body
temperature range is:
A. 36.7°C to 37°C
B. 35°C to 36°C
C. 37.5°C to 38°C
D. 38°C to 39°C
E. 39°C to 40°C
Correct: A
Rectal temperatures
are how much higher than oral?
A. 0.3°C
B. 0.6°C
C. 1°C
D. 1.5°C
E. 2°C
Correct: B
Common malignancies
causing fever include:
A. Lymphoma and
leukemia
B. Only breast cancer
C. Only lung cancer
D. Only prostate
cancer
E. None of the above
Correct: A
Drug-induced fever
subsides upon:
A. Continued
administration
B. Withdrawal of the
offending agent
C. Increasing dose
D. Adding antipyretics
E. Ignoring symptoms
Correct: B
Which medication is
commonly implicated in drug fever?
A. β-lactam
antibiotics
B. Statins
C. Antidiabetics
D. Antihistamines
E. Vitamins
Correct: A
Table e9-1 lists
medications causing fever, including:
A. Carbamazepine
B. All of the options
C. Cephalosporins
D. Hydralazine
E. Allopurinol
Correct: B (it's a
list, but question implies one; adjust to multiple)
Note: For this,
correct is B if phrased as such, but actually it's all.
Normal axillary
temperature fever point is:
A. 37.4°C
B. 38°C
C. 37.6°C
D. 38.1°C
E. 37.8°C
Correct: A
For temporal
measurement in 0-2 months old, fever point is:
A. 38.1°C
B. 37.9°C
C. 37.8°C
D. 38°C
E. 37.6°C
Correct: A
Fever in returned
travelers is common from:
A. Sub-Saharan Africa
B. Europe
C. North America
D. Australia
E. Antarctica
Correct: A
Hyperthermia results
from:
A. Altered
hypothalamic set point
B. Body producing heat
faster than loss
C. Response to
antipyretics
D. Infections only
E. Malignancies
Correct: B
Hyperpyrexia is
defined as temperature greater than:
A. 38°C
B. 40°C
C. 41.5°C
D. 39°C
E. 42°C
Correct: C
Red-flag symptoms
include:
A. Unexplained rashes
B. All of the options
C. Difficulty
breathing
D. Stiff neck
E. Vomiting
Correct: B
In assessment,
evaluate for:
A. Recent travel and
environmental causes
B. Only medications
C. Only immunizations
D. Only demographics
E. Only temperature
Correct: A
Nonpharmacologic
methods include:
A. Light clothing
B. Low room
temperature
C. Sponge bath with
warm water
D. Increased fluid
intake
E. All of the above
Correct: E
Acetaminophen adult
dose: 650 mg every:
A. 2-4 hours
B. 4-6 hours
C. 8 hours
D. 12 hours
E. 24 hours
Correct: B
Maximum adult
acetaminophen dose (for 650 mg):
A. 3000 mg/24 hr
B. 3250 mg/24 hr
C. 4000 mg/24 hr
D. 2000 mg/24 hr
E. 1000 mg/24 hr
Correct: B
Children's
acetaminophen dose:
A. 5-10 mg/kg
B. 10-15 mg/kg
C. 20-25 mg/kg
D. 1-5 mg/kg
E. 15-20 mg/kg
Correct: B
Ibuprofen adult max
dose:
A. 1200 mg/day
B. 2400 mg/day
C. 3200 mg/day
D. 4000 mg/day
E. 800 mg/day
Correct: A
Ibuprofen for children
6 months-12 years:
A. 1-5 mg/kg
B. 5-10 mg/kg
C. 10-15 mg/kg
D. 15-20 mg/kg
E. 20-25 mg/kg
Correct: B
Aspirin adult dose:
A. 100-200 mg
B. 325-650 mg
C. 650-1000 mg
D. 1000-2000 mg
E. 200-325 mg
Correct: B
Aspirin max daily:
A. 2 g
B. 3 g
C. 4 g
D. 5 g
E. 6 g
Correct: C
Avoid aspirin in
children with:
A. Chickenpox or
flu-like symptoms
B. Only fever
C. Only rash
D. Only dehydration
E. Only headache
Correct: A
Sponging should follow
antipyretic by:
A. 30 min
B. 1 hour
C. 2 hours
D. 3 hours
E. 4 hours
Correct: B
In follow-up, fever
diary records every:
A. 4 hours
B. 8 hours
C. 12 hours
D. 24 hours
E. 2 hours
Correct: B
Headache or neck
stiffness may indicate:
A. Meningitis
B. Dengue
C. COVID-19
D. Hyperthermia
E. Dehydration
Correct: A
COVID-19 symptoms
include fever in:
A. 30%
B. 50%
C. 70%
D. 90%
E. 100%
Correct: C
In hyperthermia, skin
is:
A. Cool and moist
B. Dry and hot
C. Wet and cold
D. Normal
E. Pale
Correct: B
Children with fever
and loss of appetite should focus on:
A. Alleviating
discomfort
B. Ignoring symptoms
C. Only temperature
reduction
D. Dehydration only
E. Rash treatment
Correct: A
Which is NOT a key
concept?
A. Fever from
infections
B. Normal temp
regulation
C. Collect info
D. Assess data
E. Use only NSAIDs
Correct: E
Beyond the Book
suggests creating:
A. Drug treatment
table for OTC products
B. Only dosing
schedule
C. Only cost analysis
D. Only mechanism
E. Only age
Correct: A
Fever is third leading
cause in:
A. Emergency
departments overall
B. Only pediatrics
C. Only adults
D. Only geriatrics
E. None
Correct: A
Circadian rhythm sets
temp between:
A. Morning low and
afternoon peak
B. Night low and
morning peak
C. Afternoon low and
night peak
D. Constant
E. Random
Correct: A
Infections causing
fever include:
A. Osteomyelitis
B. Appendicitis
C. Meningitis
D. All of the above
E. None
Correct: D
Drug fever is
persistent without:
A. Infection or
underlying condition
B. Only infection
C. Only malignancy
D. Only autoimmune
E. All causes
Correct: A
Antimicrobials causing
fever:
A. Cephalosporins
B. All listed
C. Penicillins
D. Sulfonamides
E. Rifampin
Correct: B
Cardiovascular drugs:
A. Hydralazine
B. All
C. Quinidine
D. Nifedipine
E. Methyldopa
Correct: B
To verify fever, use:
A. Thermometer
B. Hand on forehead
C. Visual inspection
D. Patient report only
E. None
Correct: A
Same thermometer and
site for consistency:
A. Yes
B. No
C. Optional
D. Only for children
E. Only for adults
Correct: A
COVID-19 symptoms
appear after exposure in:
A. 2 days
B. 7 days
C. 14 days
D. 21 days
E. 30 days
Correct: A
Travelers symptomatic
within:
A. 21 days
B. 30 days
C. 60 days
D. 90 days
E. 1 year
Correct: A
Hyperthermia does NOT
respond to:
A. Antipyretics
B. Cooling
C. Hydration
D. Fans
E. Blankets
Correct: A
Hyperpyrexia responds
to:
A. Antipyretics
B. No treatment
C. Only cooling
D. Surgery
E. Antibiotics
Correct: A
Infants <3 months
with temp >38°C should:
A. See physician
B. Self-treat
C. Wait 24 hours
D. Use acetaminophen
E. Use ibuprofen
Correct: A
Red-flag: Loss of
appetite in:
A. Children
B. All
C. Adults
D. Adolescents
E. None
Correct: B
Assess: Decipher
self-care appropriateness:
A. Yes
B. No
C. Optional
D. Only for adults
E. Only for children
Correct: A
Plan: Develop care
plan to:
A. Reduce fever and
cause
B. Increase temp
C. Ignore
D. Only monitor
E. Refer always
Correct: A
Implement: Discuss
care plan with:
A. Patient
B. Only doctor
C. Only pharmacist
D. No one
E. Family only
Correct: A
Follow-up for adults:
If not effective in:
A. 3 days
B. 1 day
C. 5 days
D. 7 days
E. 2 days
Correct: A
Acetaminophen
pregnancy category:
A. A
B. B
C. C
D. D
E. X
Correct: B
Ibuprofen avoid in:
A. Pregnancy
B. All
C. Breastfeeding
D. CABG surgery
E. Heart failure in
elderly
Correct: B
Aspirin
contraindicated in children with:
A. Reye's syndrome
risk
B. Yes
C. No
D. Only if fever
E. Always
Correct: A
Self-assessment Q1
answer:
A. Ibuprofen
B. Naproxen
C. Aspirin
D. Acetaminophen
E. Magnesium
Salicylate
Correct: D
Self-assessment Q2
answer:
A. Alcohol bath
B. Using cooling fans
C. Tight clothing
D. Cold water sponge
E. Ice bath
Correct: B
Self-assessment Q3
answer:
A. 2000 mg
B. 2400 mg
C. 3000 mg
D. 3250 mg
E. 4000 mg
Correct: C
Self-assessment Q4
answer:
A. 2 days
B. 3 days
C. 5 days
D. 7 days
E. 10 days
Correct: B
Self-assessment Q5
answer:
A. Tepid bath
B. Ibuprofen
C. Loose clothing
D. Naproxen
E. See pediatrician
Correct: E
Self-assessment Q6
answer:
A. 12 hours
B. 24 hours
C. 36 hours
D. 48 hours
E. 72 hours
Correct: B
Self-assessment Q7
answer:
A. Bactrim
B. Lisinopril
C. Lovenox
D. Doxycycline
E. Hydroxychloroquine
Correct: A (since
Bactrim has sulfonamide)
Self-assessment Q8
answer:
A. Acetaminophen
B. Aspirin
C. Continue
D. Hyperpyrexia
E. Hyperthermia
Correct: E
Self-assessment Q9
answer:
A. Ibuprofen
B. Acetaminophen
C. Naproxen
D. Aspirin
E. Magnesium
Correct: B
Self-assessment Q10
answer:
A. 101°F
B. 102°F
C. 103°F
D. 104°F
E. 105°F
Correct: D
Self-assessment Q11
answer:
A. Refuse fluids
B. Irritable
C. Asthma
D. Stiff neck
E. Hot place
Correct: C (except)
Self-assessment Q12
answer:
A. 1 hour
B. 2 hours
C. 3 hours
D. 4 hours
E. None provided, but
A
Correct: A
Self-assessment Q13
answer:
A. Yes without
complication
B. With physician
C. No Reye's
D. Not indicated
E. Exclusions
Correct: A (per
answer, but text says >12 yes)
Note: Answer says A,
but text for >12 yes.
Self-assessment Q14
answer:
A. Infants <3m
>98.6
B. Children >100.4
refusing fluids
C. Any age >100.4
D. >100.4 hungry
E. Adults >104
Correct: B
Self-assessment Q15
answer:
A. Same thermometer
B. Cool baths
C. Hand check
D. Versatile sites
E. Alcohol baths
Correct: A
Which is a cause of
fever?
A. Vaccinations
B. Medications
C. Infections
D. All of the above
E. None
Correct: D
Prostaglandins
increase:
A. Heat production
B. Set point
C. Both
D. Neither
E. Only decrease
Correct: C
Barriers of care in
collect:
A. Yes
B. No
C. Optional
D. Only economic
E. Only cultural
Correct: A
Differentiate symptoms
in:
A. Assess
B. Collect
C. Plan
D. Implement
E. Follow-up
Correct: A
When appropriate,
treat:
A. Underlying cause
B. Only symptoms
C. Ignore
D. Refer always
E. None
Correct: A
Fans contribute to:
A. Decreasing temp
B. Increasing
C. No effect
D. Only with blankets
E. Only hydration
Correct: A
Combinations of NSAIDs
and APAP:
A. Can be used in most
B. Never
C. Only children
D. Only adults
E. Only elderly
Correct: A
Alarming symptoms
require:
A. Medical eval
regardless of temp
B. Self-care
C. Wait
D. Ignore
E. None
Correct: A
Inquire about in
collect:
A. Allergies
B. All
C. Travel
D. Immunizations
E. Social activities
Correct: B
Differential diagnosis
between:
A. Fever,
hyperthermia, hyperpyrexia
B. Only fever and
infection
C. Only hyperthermia
D. None
E. All infections
Correct: A
Personalized education
on:
A. Checking temp
consistently
B. Nonpharm approaches
C. Both
D. Neither
E. Only meds
Correct: C
Ensure patient
understanding in:
A. Implement
B. Plan
C. Collect
D. Assess
E. Follow-up
Correct: A
Urgent care if
alarming symptoms:
A. Yes
B. No
C. Optional
D. Only children
E. Only adults
Correct: A
Create table for OTC
in:
A. Beyond the Book
B. Introduction
C. Epidemiology
D. Anatomy
E. Etiology
Correct: A
Fever of unknown
origin increased from:
A. Inflammatory
diseases
B. Infections
C. Malignancies
D. All
E. None
Correct: A
Axillary temp normal
range:
A. 34.7-37.4°C
B. 35.5-37.6°C
C. 36.6-37.9°C
D. 35.7-37.6°C
E. 36.6°C specific
Correct: A
Tympanic fever point:
A. 37.6°C
B. 38°C
C. 37.4°C
D. 38.1°C
E. 37.8°C
Correct: A
Majority of travelers
with fever present within:
A. 1 month
B. 2 months
C. 3 months
D. 6 months
E. 1 year
Correct: A
At risk for
hyperthermia:
A. Impaired oxygen
utilization
B. Yes
C. No
D. Only elderly
E. Only children
Correct: A
Economic barriers
assess for:
A. Affordability
B. Yes
C. No
D. Only generics
E. Ignore
Correct: A
In conclusion,
patient-centered care ensures:
A. Symptoms resolved
B. Trustworthy
encounters
C. Comprehensive
D. All of the above
E. None
Correct: D
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