100 Ready-to-Use MCQs on Fever Management (Based on Chapter 9: Fever from DiPiro's Pharmacotherapy) Nehad J. Ahmed Written by: Claude.ai

 

100 Ready-to-Use MCQs on Fever Management (Based on Chapter 9: Fever from DiPiro's Pharmacotherapy)

 

Nehad J. Ahmed

 

Written by: Claude.ai

 

 


Temperature and Definitions

  1. What is the normal oral body temperature range?
    • A. 35.5°C to 36.7°C
    • B. 36.7°C to 37°C
    • C. 37°C to 37.5°C
    • D. 37.5°C to 38°C
  2. How much higher are rectal temperatures compared to oral temperatures?
    • A. 0.3°C (0.5°F)
    • B. 0.6°C (1°F)
    • C. 1°C (1.8°F)
    • D. 1.5°C (2.7°F)
  3. What is the fever threshold for rectal temperature measurements?
    • A. 37.6°C (99.6°F)
    • B. 37.9°C (100.2°F)
    • C. 38°C (100.4°F)
    • D. 38.5°C (101.3°F)
  4. Hyperpyrexia is defined as a fever greater than:
    • A. 39°C (102.2°F)
    • B. 40°C (104°F)
    • C. 41°C (105.8°F)
    • D. 41.5°C (106.7°F)
  5. What is the fever point for axillary temperature measurements?
    • A. 37°C (98.6°F)
    • B. 37.4°C (99.4°F)
    • C. 37.9°C (100.2°F)
    • D. 38°C (100.4°F)

Pathophysiology

  1. Where is the thermoregulatory center located?
    • A. Posterior hypothalamus
    • B. Anterior hypothalamus
    • C. Medulla oblongata
    • D. Cerebral cortex
  2. What causes the increase in hypothalamic temperature set point during fever?
    • A. Cytokines
    • B. Leukotrienes
    • C. Prostaglandins
    • D. Histamine
  3. How does fever differ from hyperthermia?
    • A. Fever involves a reset hypothalamic set point
    • B. Hyperthermia responds to antipyretics
    • C. Fever occurs more rapidly
    • D. Hyperthermia is always more dangerous
  4. What characterizes hyperthermia?
    • A. Controlled elevation of body temperature
    • B. Uncontrolled rise in body temperature
    • C. Decreased metabolic rate
    • D. Lowered hypothalamic set point
  5. Which statement about hyperpyrexia is correct?
    • A. It does not respond to antipyretics
    • B. It responds to antipyretics
    • C. It only occurs with bacterial infections
    • D. It is less dangerous than regular fever

Etiology

  1. According to the National Ambulatory Medical Care Survey, fever is what leading cause of emergency department visits in all patients?
    • A. First
    • B. Second
    • C. Third
    • D. Fourth
  2. In patients younger than 15 years old, fever is the _____ leading cause of emergency department visits.
    • A. Leading cause
    • B. Second leading cause
    • C. Third leading cause
    • D. Fourth leading cause
  3. Which of the following medication classes is MOST commonly implicated in drug-induced fever?
    • A. ACE inhibitors
    • B. β-lactam antibiotics
    • C. Calcium channel blockers
    • D. Proton pump inhibitors
  4. Which antibiotic is listed as a medication that can cause fever?
    • A. Amoxicillin
    • B. Azithromycin
    • C. Doxycycline
    • D. Metronidazole
  5. Which cardiovascular medication can cause drug-induced fever?
    • A. Amlodipine
    • B. Atenolol
    • C. Hydralazine
    • D. Losartan

Drug-Induced Fever

  1. What characterizes drug-induced fever?
    • A. Persistent fever with an identified infection
    • B. Persistent fever without infection or another underlying condition
    • C. Intermittent fever with drug administration
    • D. Fever that persists after drug withdrawal
  2. Which anticonvulsant is commonly implicated in drug-induced fever?
    • A. Levetiracetam
    • B. Gabapentin
    • C. Phenytoin
    • D. Lamotrigine
  3. Which of the following is NOT listed as causing drug-induced fever?
    • A. Allopurinol
    • B. Nitrofurantoin
    • C. Methyldopa
    • D. Omeprazole
  4. What happens to temperature after withdrawal of the offending agent in drug-induced fever?
    • A. Temperature increases
    • B. Temperature fluctuates
    • C. Temperature remains normal
    • D. Temperature decreases gradually over weeks
  5. Which H2 antagonist can cause fever?
    • A. Famotidine
    • B. Nizatidine
    • C. Ranitidine
    • D. Roxatidine

Patient Assessment

  1. Within how many days do symptoms typically appear after COVID-19 exposure?
    • A. As soon as 2 days
    • B. 5-7 days
    • C. 10-14 days
    • D. 21 days
  2. For travelers returning from tropical areas, the majority who develop fever present within:
    • A. 1 week
    • B. 2 weeks
    • C. 1 month
    • D. 3 months
  3. Which regions are MORE commonly associated with travel-related fever?
    • A. Northern Europe
    • B. Sub-Saharan Africa
    • C. North America
    • D. Australia
  4. What percentage of COVID-19 patients reported symptoms of fever, cough, or shortness of breath?
    • A. 50%
    • B. 60%
    • C. 70%
    • D. 80%
  5. When collecting information about fever, what is the preferred method to verify fever?
    • A. Feeling the forehead
    • B. Patient's subjective report
    • C. Reading from a thermometer
    • D. Observing skin color

Red Flag Symptoms - Pediatrics

  1. Infants younger than what age with temperature above 38°C (100.4°F) should see a physician irrespective of symptoms?
    • A. 1 month
    • B. 2 months
    • C. 3 months
    • D. 6 months
  2. Children of any age with a temperature above what threshold should see a physician regardless of symptoms?
    • A. 38°C (100.4°F)
    • B. 39°C (102.2°F)
    • C. 40°C (104°F)
    • D. 41°C (105.8°F)
  3. Which is a red flag symptom in children with fever?
    • A. Mild cough
    • B. Slight nasal congestion
    • C. Refusing oral fluids
    • D. Normal appetite
  4. A child with fever who is drooling excessively and unable to swallow should:
    • A. Continue home treatment
    • B. See a physician immediately
    • C. Increase fluid intake
    • D. Wait 48 hours
  5. Which symptom with fever requires immediate medical attention in children?
    • A. Mild fatigue
    • B. Stiff neck
    • C. Decreased appetite
    • D. Mild irritability

Red Flag Symptoms - General

  1. Adults with high fever above what temperature should see a physician irrespective of symptoms?
    • A. 39°C (102.2°F)
    • B. 40°C (104°F)
    • C. 41°C (105.8°F)
    • D. 42°C (107.6°F)
  2. Patients with fever and which condition should see a physician immediately?
    • A. Mild headache
    • B. Taking steroids or immunocompromised
    • C. History of seasonal allergies
    • D. Controlled hypertension
  3. Which is a red flag symptom requiring immediate medical evaluation?
    • A. Slight dizziness
    • B. Unexplained dermatologic rash
    • C. Mild sore throat
    • D. Watery eyes
  4. Patients with fever and which recent history should seek immediate care?
    • A. Recent vaccination
    • B. Recent chemotherapy
    • C. Recent mild exercise
    • D. Recent dietary changes
  5. Changes in mental status with fever indicate:
    • A. Normal response
    • B. Need for immediate medical evaluation
    • C. Adequate hydration needed
    • D. Medication dose adjustment

Acetaminophen

  1. What is the preferred agent to reduce fever in most patients?
    • A. Ibuprofen
    • B. Aspirin
    • C. Acetaminophen
    • D. Naproxen
  2. What is the adult dose of acetaminophen for fever?
    • A. 325 mg every 4-6 hours
    • B. 500 mg every 4-6 hours
    • C. 650 mg every 4-6 hours
    • D. 1000 mg every 4-6 hours
  3. What is the maximum daily dose of acetaminophen when using 650 mg tablets?
    • A. 2600 mg
    • B. 3000 mg
    • C. 3250 mg
    • D. 4000 mg
  4. What is the maximum daily dose of acetaminophen when using 500 mg tablets?
    • A. 2500 mg
    • B. 3000 mg
    • C. 3250 mg
    • D. 4000 mg
  5. How does acetaminophen reduce fever?
    • A. By inhibiting cyclooxygenase peripherally
    • B. By inhibiting prostaglandin production in the CNS
    • C. By direct cooling effect
    • D. By increasing heat loss

Acetaminophen - Pediatrics & Special Populations

  1. What is the pediatric dose of acetaminophen for fever?
    • A. 5-10 mg/kg every 4-6 hours
    • B. 10-15 mg/kg every 4-6 hours
    • C. 15-20 mg/kg every 4-6 hours
    • D. 20-25 mg/kg every 4-6 hours
  2. What is the maximum daily dose of acetaminophen in infants?
    • A. 50 mg/kg/day
    • B. 75 mg/kg/day
    • C. 100 mg/kg/day
    • D. 125 mg/kg/day
  3. What is the maximum daily dose of acetaminophen in children?
    • A. 75 mg/kg/day or 1625 mg/day, whichever is less
    • B. 100 mg/kg/day or 1625 mg/day, whichever is less
    • C. 100 mg/kg/day or 2000 mg/day, whichever is less
    • D. 125 mg/kg/day or 2000 mg/day, whichever is less
  4. What is the FDA pregnancy category for acetaminophen?
    • A. Category A
    • B. Category B
    • C. Category C
    • D. Category D
  5. In which condition is acetaminophen contraindicated?
    • A. Mild renal impairment
    • B. Active and severe hepatic impairment
    • C. Pregnancy
    • D. Lactation

Ibuprofen

  1. What is the adult dose of ibuprofen for fever?
    • A. 100-200 mg every 4-6 hours
    • B. 200-400 mg every 4-6 hours
    • C. 400-600 mg every 4-6 hours
    • D. 600-800 mg every 4-6 hours
  2. What is the maximum daily dose of ibuprofen in adults?
    • A. 800 mg
    • B. 1000 mg
    • C. 1200 mg
    • D. 1600 mg
  3. What is the pediatric dose of ibuprofen (6 months to 12 years)?
    • A. 2-5 mg/kg every 6-8 hours
    • B. 5-10 mg/kg every 6-8 hours
    • C. 10-15 mg/kg every 6-8 hours
    • D. 15-20 mg/kg every 6-8 hours
  4. What is the maximum number of ibuprofen doses per day in children?
    • A. 3 doses
    • B. 4 doses
    • C. 5 doses
    • D. 6 doses
  5. Which ibuprofen formulation should children younger than 2 years use?
    • A. 100 mg/5 mL suspension
    • B. 50 mg/1.25 mL suspension
    • C. 200 mg chewable tablets
    • D. 100 mg chewable tablets

Ibuprofen - Contraindications

  1. Why should ibuprofen be avoided in older adults with heart failure?
    • A. Increased bleeding risk
    • B. Possible fluid retention and heart failure exacerbation
    • C. Drug interactions
    • D. Reduced efficacy
  2. In which chronic kidney disease stage should ibuprofen be avoided in older adults?
    • A. Stage 2 or 3
    • B. Stage 3 or 4
    • C. Stage 4 or 5
    • D. All stages
  3. Can ibuprofen be used during pregnancy?
    • A. Yes, in all trimesters
    • B. Yes, but only in first trimester
    • C. No, risks to fetus cannot be ruled out
    • D. Yes, with physician approval
  4. What serious cardiovascular risk is associated with NSAIDs like ibuprofen?
    • A. Bradycardia
    • B. Hypotension
    • C. Thrombotic events and myocardial infarction
    • D. Arrhythmias
  5. Ibuprofen cannot be used in patients undergoing:
    • A. Dental surgery
    • B. Coronary artery bypass graft surgery
    • C. Cataract surgery
    • D. Minor dermatologic procedures

Aspirin

  1. What is the adult dose of aspirin for fever?
    • A. 250-500 mg every 4-6 hours
    • B. 325-650 mg every 4-6 hours
    • C. 500-1000 mg every 4-6 hours
    • D. 650-975 mg every 4-6 hours
  2. What is the maximum daily dose of aspirin for fever in adults?
    • A. 3 g
    • B. 4 g
    • C. 5 g
    • D. 6 g
  3. At what age can children safely take aspirin for fever?
    • A. 6 years or older
    • B. 10 years or older
    • C. 12 years or older
    • D. 16 years or older
  4. Why should aspirin not be given to children with flu-like symptoms?
    • A. Increased bleeding risk
    • B. Risk of Reye's syndrome
    • C. Ineffective in children
    • D. Causes gastric upset
  5. In which condition should aspirin be avoided in children?
    • A. Common cold
    • B. Mild headache
    • C. Chickenpox or flu-like symptoms
    • D. Mild fever without other symptoms

Nonpharmacologic Management

  1. Which nonpharmacologic method is appropriate for fever management?
    • A. Ice baths
    • B. Alcohol baths
    • C. Wearing light clothing
    • D. Hot compresses
  2. Why should alcohol baths NOT be used for fever?
    • A. Ineffective
    • B. Potential for shock
    • C. Causes skin irritation
    • D. Too expensive
  3. What type of water should be used for sponge baths?
    • A. Cold water
    • B. Ice water
    • C. Warm/tepid water
    • D. Hot water
  4. When should sponging be stopped?
    • A. After 5 minutes
    • B. When patient feels cold
    • C. If patient begins shivering
    • D. After 15 minutes
  5. How long after antipyretic therapy should sponging follow?
    • A. Immediately
    • B. 30 minutes
    • C. 1 hour
    • D. 2 hours

Nonpharmacologic Management - Continued

  1. Why should sponging follow antipyretic therapy?
    • A. To enhance antipyretic absorption
    • B. To reduce the hypothalamic set point first
    • C. To prevent medication side effects
    • D. To improve patient comfort immediately
  2. What should patients do to prevent dehydration during fever?
    • A. Restrict fluids
    • B. Increase fluid intake
    • C. Take diuretics
    • D. Drink only cold beverages
  3. Which room temperature is recommended for fever management?
    • A. Very cold temperature
    • B. Normal room temperature
    • C. Low room temperature to stay comfortable
    • D. Elevated temperature
  4. What is the purpose of using cooling fans in fever management?
    • A. Primary treatment
    • B. To contribute to decreasing body temperature
    • C. To replace antipyretics
    • D. To prevent sweating
  5. Should cooling blankets be used alone for fever?
    • A. Yes, they are very effective alone
    • B. No, should only be used along with antipyretics
    • C. Yes, but only in adults
    • D. No, they should never be used

Follow-Up & Monitoring

  1. How long should adults use OTC treatment before seeking medical care if no improvement?
    • A. 1 day
    • B. 2 days
    • C. 3 days
    • D. 5 days
  2. How long should children 2 years or older use OTC treatment before seeking care?
    • A. 24 hours
    • B. 48 hours
    • C. 72 hours
    • D. 96 hours
  3. How long should children younger than 2 years use OTC treatment before seeking care?
    • A. 12 hours
    • B. 24 hours
    • C. 48 hours
    • D. 72 hours
  4. What should patients keep to track fever progression?
    • A. Medication log only
    • B. Symptom diary only
    • C. Fever diary with temperatures every 8 hours
    • D. Weekly temperature log
  5. How often should temperatures be recorded in a fever diary?
    • A. Every 4 hours
    • B. Every 8 hours
    • C. Every 12 hours
    • D. Once daily

Differential Diagnosis

  1. What symptom distinguishes meningitis in patients with fever?
    • A. Cough
    • B. Headache or neck stiffness
    • C. Abdominal pain
    • D. Rash
  2. Fever with diarrhea and abdominal pain may indicate:
    • A. Viral upper respiratory infection
    • B. Bacterial infection
    • C. Drug-induced fever
    • D. Hyperthermia
  3. What condition might prolonged fever with rash and myalgias indicate in travelers?
    • A. Malaria
    • B. Typhoid fever
    • C. Dengue fever
    • D. Yellow fever
  4. Which diagnostic test may be needed for suspected meningitis?
    • A. Blood culture
    • B. Lumbar puncture
    • C. Chest X-ray
    • D. Urinalysis
  5. In hyperthermia, which symptom is commonly seen?
    • A. Moist skin
    • B. Dry and hot skin
    • C. Pale skin
    • D. Cyanotic skin

Hyperthermia vs. Fever

  1. Do antipyretics work for hyperthermia?
    • A. Yes, very effectively
    • B. No, they are not effective
    • C. Yes, but high doses needed
    • D. Sometimes effective
  2. What causes hyperthermia?
    • A. Infection
    • B. Body takes on heat faster than it can lose it
    • C. Increased hypothalamic set point
    • D. Immune response
  3. How can hyperthermia be distinguished from fever?
    • A. Fever is always higher
    • B. Hyperthermia doesn't respond to antipyretics
    • C. Hyperthermia causes more sweating
    • D. Fever occurs more rapidly
  4. What might cause hyperthermia?
    • A. Viral infection
    • B. Bacterial infection
    • C. Exposure to extremely high temperatures
    • D. Autoimmune disease
  5. What cooling technique can be used for hyperthermia?
    • A. Antipyretics only
    • B. Cool blankets and fans
    • C. Warm baths
    • D. No treatment needed

Patient Care Process

  1. What information should be collected about recent activities?
    • A. Only exercise history
    • B. Only dietary habits
    • C. Recent travel, climate, and social activities
    • D. Only work schedule
  2. Why should immunization history be collected?
    • A. To update records
    • B. Vaccinations can cause moderate-to-severe illness with fever
    • C. Required by law
    • D. To check insurance coverage
  3. What patient-specific factors should be assessed?
    • A. Only medical history
    • B. Only medication list
    • C. Religious/cultural barriers to therapy
    • D. Only laboratory values
  4. Why assess economic barriers?
    • A. For insurance purposes
    • B. May alter care decisions based on cost
    • C. Required documentation
    • D. Statistical purposes
  5. When should the same thermometer and measurement site be used?
    • A. Only for children
    • B. Only for initial reading
    • C. During the course of fever
    • D. Not necessary

Combination Therapy & General

  1. Can acetaminophen and ibuprofen be used together?
    • A. Never
    • B. Yes, in most but not all patients
    • C. Only in adults
    • D. Only with physician approval
  2. How are all antipyretics dosed for fever?
    • A. Around the clock
    • B. With meals
    • C. On an as-needed basis
    • D. At bedtime only
  3. What should guide pediatric dosing when possible?
    • A. Age
    • B. Height
    • C. Weight
    • D. Symptom severity
  4. What must be considered when selecting fever treatment?
    • A. Only efficacy
    • B. Only safety
    • C. Drug interactions with current medications
    • D. Only cost
  5. What laboratory values are helpful if available?
    • A. Complete blood count and kidney/liver function
    • B. Only glucose levels
    • C. Only electrolytes
    • D. Lipid panel only

Clinical Scenarios

  1. A patient reports taking antipyretics with no decrease in temperature after heat exposure. This suggests:
    • A. Wrong medication
    • B. Insufficient dose
    • C. Possible hyperthermia
    • D. Drug resistance
  2. When should generic equivalents be recommended?
    • A. Never
    • B. Only for brand preference
    • C. To improve adherence due to affordability
    • D. Only for insured patients
  3. What should be discussed with patients about the care plan?
    • A. Only medication names
    • B. Goals of therapy, adverse effects, interactions
    • C. Only the cost
    • D. Only follow-up timing
  4. Patient agreement with the treatment plan should be:
    • A. Assumed
    • B. Documented only
    • C. Ensured through open-ended dialogue
    • D. Not necessary
  5. What indicates a need for urgent/emergent care during follow-up?
    • A. Mild improvement
    • B. Stable temperature
    • C. Presence of alarming symptoms
    • D. Medication side effects

 

تعليقات

المشاركات الشائعة من هذه المدونة

Tips on how to write a meta-analysis by Dr. Nehad Jaser

Centers for Disease Control and Prevention (CDC) categorizes germs into three main categories

The history of herbal medicine